Guest editors Mark Acierno and Mary Labato highlight important areas in kidney failure and renal replacement therapies for all small animal practitioners. Topics include continuous renal replacement therapy, intermittent hemodialysis/peritoneal dialysis, acute kidney injury, chronic kidney disease, protein losing nephropathy, hypertension in kidney disease, intermittent hemodialysis, equipment commonly used in veterinary dialysis/vascular access, anticoagulation in intermittent hemodialysis, urea kinetics and dialysis prescriptions, removal of toxins and drugs, nutrition in the renal failure/dialysis patient, dialysate, water quality and testing, and much more